Serum α-L-fucosidase

The α-L-fucosidase is a lysosomal acid hydrolase that catalyzes a bioactive macromolecular hydrolase such as a glycoprotein or a glycolipid containing a fucosyl group. It is widely distributed in human tissue cells, blood and body fluids. Participate in the metabolism of glycoproteins, glycolipids and oligosaccharides in the body. Because of the significant increase in α-L-fucosidase in patients with liver cancer, it is currently considered to be a new tumor marker for primary liver cancer. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reduces fucoid accumulation caused by a lack of hereditary α-L-fucosidase. Normal value: Serum α-L-fucosidase: 6.80-±1.49u/g Above normal: Increased in primary liver cancer, metastatic liver cancer, cirrhosis, acute hepatitis and so on. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Normal value Enzyme rate method (37 ° C) (6.80 ± 1.49) U / L. Clinical significance Abnormal result 1. Reduce the fucoid accumulation disease caused by the lack of hereditary α-L-fucosidase. 2, elevated in primary liver cancer, metastatic liver cancer, cirrhosis, acute hepatitis and so on. 3, the emergence of r-GTPII zone seen in primary and secondary liver cancer. The r-GTPI', II/II' zone is a specific new band of liver cancer, and other hepatobiliary diseases (metastasis cirrhosis, alcoholic hepatitis, cholangiocarcinoma) do not appear in the new zone. 4. The damage of hepatic parenchyma cells is mainly caused by the increase of r-GTP1. The extrahepatic biliary tract disease is mainly r-GTP2, and the r-GTP4 region can also occur, and r-GTP2>r-GTP1>r-GTP3. Low results may be diseases: high results of fucoside storage disease may be diseases: metastatic liver cancer, primary liver cancer considerations First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Immediately after venous blood collection, the test method was determined by the enzyme speed method. Not suitable for the crowd Special diseases: Patients with hematopoietic dysfunction, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.