Plasma valine

The plasma amino acid concentration of normal people fluctuates day and night, generally peaking between 8 and 10 in the morning and trough at midnight. The determination of amino acids and their products is of great significance for the diagnosis of congenital or acquired metabolic diseases. Clinical determination of plasma proline, to avoid the effects of food digestion and absorption, should be taken in the early morning on an empty stomach. Specimens should not be used for hemolysis to avoid false increases due to the entry of amino acids into the plasma in red blood cells. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: The plasma amino acid concentration of normal people fluctuates day and night, generally peaking between 8 and 10 in the morning and trough at midnight. Normal value: Plasma proline: 207.78-242.34μmol/L Above normal: Increased in hyperprolineemia. negative: Positive: Tips: Blood collection in the morning is good. Normal value 207.78 to 242.34 μmol/L. Clinical significance Increased in hyperprolineemia. Hyperprolineemia is due to the lack of proline transaminase in patients, the breakdown of proline in the body, the specific increase in blood and urine proline concentration, the disease is autosomal recessive. Shortly after birth, the child developed severe vomiting and developed a dangerous ketoacidosis, which caused drowsiness and coma. It was characterized by spitting or exuding a strong stench like a sweaty foot from the body during the attack. The above symptoms are most intense from 1 to 2 weeks after birth, and gradually become intermittent afterwards, and are prone to attack when infected or ingested high protein. The patient's white blood cells have a disorder of proline transamination, causing developmental delay and mental retardation. High results may be diseases: developmental delay, mental retardation considerations 1. The plasma amino acid concentration of normal people fluctuates day and night, with a peak at 8 to 10 in the morning and a trough at midnight. When taking blood, it is necessary to avoid the effects of digestion and absorption of food. It is better to take blood on an empty stomach in the morning. 2. If the specimen is not suitable for hemolysis, it may lead to a false increase in the measurement results. Inspection process The blood was collected on an empty stomach in the morning, and the measurement was performed by the same fluorescence method. Not suitable for the crowd no. Adverse reactions and risks no.