ceruloplasmin (CP)

Ceruloplasmin is a copper-containing protein that is blue, so it is called ceruloplasmin, also known as iron oxidase. It is mainly synthesized by the liver. Its role is to regulate the distribution of copper in various parts of the body, synthesize copper-containing enzyme protein, have antioxidant effects, and have oxidase activity. The ceruloplasmin assay has certain significance for the diagnosis of certain diseases such as liver, gallbladder and kidney. Basic Information Specialist classification: Digestive examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: 1 Wilson disease is hepatolenticular degeneration (the most valuable diagnostic indicator). 2 malnutrition nephrotic syndrome, malabsorption syndrome, protein leakage gastrointestinal disease, nephrotic syndrome, hypoproteinemia. 3 primary biliary cirrhosis, primary biliary atresia and so on. 4 newborn, immature children. Normal value: Plasma CP (newborn): 10-300mg/L Plasma CP (6 months to 1 year old): 150-500mg/L Plasma CP (1.?-00-650mg/L) Above normal: 1 Severe infection with inflammation, hepatitis, periostitis, pyelonephritis, tuberculosis, pneumoconiosis, etc. 2 malignant tumor leukemia, malignant lymphoma, various cancers. 3 bile stasis stagnation of primary biliary stagnation cirrhosis, extrahepatic obstructive jaundice, acute hepatitis, chronic hepatitis, alcoholic cirrhosis. 4 hyperthyroidism, rheumatism, rheumatoid arthritis, aplastic anemia, myocardial infarction, postoperative and so on. 5 other acute schizophrenia, tremor sputum, homocystinuria, pregnancy, oral contraceptives. negative: Positive: Tips: It is advisable to take venous blood on an empty stomach, oral contraceptives and late pregnancy, which can increase the results of ceruloplasmin determination. Normal value Immunodiffusion Neonatal 10 ~ 300mg / L (1 ~ 30mg / dl). 6 months to 1 year old 150 to 500 mg / L (15 ~ 50 mg / dl). 1 to 12 years old, 300 to 650 mg/L (30 to 650 mg/dl). >12 years old 150 ~ 600mg / L (15 ~ 60mg / dl). Urine 6 ~ 40μg / 24h urine. Clinical significance 1. Raise (1) Severe infection with inflammation, hepatitis, periostitis, pyelonephritis, tuberculosis, pneumoconiosis, etc. (2) malignant tumor leukemia, malignant lymphoma, various cancers. (3) bile stasis primary biliary stasis cirrhosis, extrahepatic obstructive jaundice, acute hepatitis, chronic hepatitis, alcoholic cirrhosis. (4) Hyperthyroidism, rheumatism, rheumatoid arthritis, aplastic anemia, myocardial infarction, postoperative surgery, etc. (5) Other acute schizophrenia, tremor sputum, homocystinuria, pregnancy, oral contraceptives. 2, lower (1) Wilson's disease is hepatolenticular degeneration (the most valuable diagnostic indicator). (2) malnutrition nephrotic syndrome, malabsorption syndrome, protein leakage gastrointestinal disease, nephrotic syndrome, hypoproteinemia and the like. (3) Primary biliary cirrhosis, primary biliary atresia, etc. (4) Newborns, immature children. Low results may be diseases: Wilson's disease , malignant lymphoma, malabsorption syndrome, primary biliary cirrhosis 1. It is advisable to take venous blood on an empty stomach. 2, oral contraceptives and late pregnancy, can increase the results of ceruloplasmin determination. Inspection process Immediately after blood collection, the test is carried out. Not suitable for the crowd Those without examination indications should not be tested. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.