Plasma Growth Mediator Assay (SOM)

The role of the auxin medium auxin is achieved by inducing a growth-promoting peptide substance produced by hepatocytes and present in plasma. This substance is called an auxin medium. It accelerates protein synthesis, increases collagen tissue, promotes chondrocyte division, and accelerates cartilage growth and ossification. The auxin medium is a kind of polypeptide substance, which has three subtypes of A, B and C, all of which have insulin action. The auxin mediator-C in plasma induces hepatocyte synthesis and release after growth hormone acts on hepatocyte receptors. The concentration of auxin-C in plasma does not change with the pulse fluctuation of growth hormone secretion. Various factors that stimulate or inhibit the release of growth hormone can not cause the concentration of growth medium-C to change in a short time, so the plasma concentration is higher. Stable, plasma auxin mediator-C assay can be used to analyze the functional status of growth hormone, as well as differential diagnosis of growth hormone receptor genetic defects caused by auxin mediators. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reducing the lack of hereditary growth hormone receptors found in growth hormone deficiency and high growth hormone levels can also be seen in cachexia, severe malnutrition, and severe liver disease. Normal value: Plasma auxin medium (male): 0.3-1.9u/ml Plasma auxin medium (female): 0.5-2.2u/ml Plasma auxin sword?.9-5.9u/ml Above normal: Elevated in giant disease and acromegaly. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. Normal value Children 0.1~2.5u/ml. Adolescents 0.9~5.9u/ml. Male 0.3~1.9u/ml. Female o.5~2.2u/ml. Clinical significance 1. Reduce the lack of hereditary growth hormone receptors found in growth hormone deficiency and high growth hormone levels, as well as those with cachexia, severe malnutrition and severe liver disease. 2, elevated in giant disease and acromegaly. Low results may be diseases: high results of giant disease may be diseases: growth hormone deficiency, giant disease and acromegaly considerations First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Third, the results of adolescent juvenile determination may increase. Inspection process A certain amount of blood is drawn for examination and measurement. Not suitable for the crowd Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the test, and patients with a history of drug administration in the near future are prohibited. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.