Vitamin B12

Vitamin B12 is also known as cobalamin. The body usually contains 2 to 5 mg of vitamin B12. Most of it is stored in the liver, which is about 80% of the total storage in the body. The rest is found in muscle, skin and bone tissue, and a small amount is present in the lungs, kidneys and spleen. The most important function of vitamin B12 is that it is an important substance for bone marrow hematopoiesis. Basic Information Specialist classification: inspection classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reduced in megaloblastic anemia, post-gastrectomy, intestinal malabsorption, intestinal parasitic diseases, also seen in long-term vegetarians. Normal value: Vitamin B12 (plasma): 74-516pmol/L Vitamin B12 (serum adult): 103-516pmol/L Vitamin B1: 81-590pmol/L Above normal: Elevated in acute and chronic myeloid leukemia, lymphocytic leukemia, monocytic leukemia, leukocytosis, polycythemia vera, partial malignant cell tumors and liver lesions. negative: Positive: Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value Plasma; 74 ~ 516pmol / L; Serum adult: 103 ~ 516pmol / L; <60 years old: 81 to 590 pmo/L. Clinical significance Abnormal result 1, reduction: seen in megaloblastic anemia, gastrectomy, intestinal malabsorption, intestinal parasitic disease, also seen in long-term vegetarians. 2, elevated: seen in acute and chronic granulocytic leukemia, lymphocytic leukemia, monocytic leukemia, leukocytosis, polycythemia vera, some malignant cell tumors and liver lesions. Low results may be diseases: anemia caused by vitamin B12 deficiency, intestinal malabsorption syndrome, pregnancy with megaloblastic anemia, chronic gastritis, pediatric megaloblastic anemia, chronic gastritis in the elderly, chronic myeloid leukemia, liver fibrosis Laminar cancer, malabsorption syndrome after gastrectomy, subacute combined degeneration considerations Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process Immediately after venous blood collection, the test was performed by ELISA. Test operation: serum is used for detection. First, the blood is subjected to agglutination for at least half an hour, and then serum is taken. After diluting the enzyme complex with the diluent, add serum and a negative, positive control, and a control (this is a strict requirement, and its range must be within the control range). After an hour of incubation, then wash the plate, add the substrate, half an hour to avoid the light reaction and add the stop solution to complete the reaction part, then the reading. The result is judged to be negative or positive by the value. Not suitable for the crowd Inappropriate people: generally no special population. Adverse reactions and risks no.