vitamin A alcohol binding protein

Retinol-binding protein is a vitamin transporter in the blood, synthesized by the liver and widely distributed in blood, cerebrospinal fluid, urine and other body fluids. Determination of retinol binding protein can detect tubular damage in the early stage, and can sensitively reflect the degree of damage of renal proximal convoluted tubules, and can also be used as an indicator of early damage and monitoring of liver function. Basic Information Specialist classification: inspection classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Vitamin A deficiency, hypoproteinemia, malabsorption syndrome, liver disease (except for over-nutrition fatty liver), obstructive jaundice, hyperthyroidism, infection, trauma, etc. Normal value: Vitamin A alcohol binding protein (male): 36-56mg/L Vitamin A alcohol binding protein (female): 26.7-57.9mg/L Above normal: Renal insufficiency, over-nutrition fatty liver. negative: Positive: Tips: Retinol-binding protein is a vitamin transport protein in the blood, synthesized by the liver, widely distributed in blood, cerebrospinal fluid, urine and other body fluids. Normal value ELISA method, RIA method Male: 36 ~ 56mg / L (36.0 ~ 56.0μg / ml). Female: 26.7 to 57.9 mg/L (26.7 to 57.9 μg/ml). Clinical significance Clinical significance: Retinol-binding egg-binding protein is a transport protein of vitamins in the blood, which is synthesized by the liver and widely distributed in blood, cerebrospinal fluid, urine and other body fluids. Determination of retinol-binding egg-binding protein can detect tubular damage in the early stage, and can sensitively reflect the degree of damage of renal proximal convoluted tubules, and can also be used as an indicator of early damage and monitoring of liver function. Abnormal results: 1, reduction: vitamin A deficiency, hypoproteinemia, malabsorption syndrome, liver disease (except for over-nutrition fatty liver), obstructive jaundice, hyperthyroidism, infection, trauma and so on. 2, elevated: renal insufficiency, over-nutrition fatty liver. Low results may be diseases: fatty liver results may be high. Possible diseases: precautions for hyperthyroidism in children Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for examination: For the identification of liver and kidney diseases, serum prealbumin (PA) can be measured simultaneously, and the ratio of RBP/PA can be calculated (reference range is 0.40±0.1. If it is <0.425, it is usually caused by liver disease, but at 1.06±0.1. Most of them are caused by kidney disease). Inspection process Immediately after the blood sample is collected, the test is carried out. 1. Pipette 3 ml of serum into a 25 ml glass stopper grind cone, add 3 ml of absolute ethanol, and rotate while mixing. Add 6 ml of petroleum ether, cover with a glass stopper, and mix thoroughly for about several minutes. 2. Transfer to a 15 ml stoppered centrifuge tube, stopper, and centrifuge at low speed (about 900 g) for about 1 to 2 minutes. 3. All the petroleum ether layers are sucked out and placed in a test tube with a stopper, to be tested. 4. Using 450nm wavelength, 1cm cuvette, correct the absorbance to 0 points with petroleum ether, read the absorbance of the above extract, check the standard curve, and find the content of serum β-carotene (retain the colorimetric liquid for vitamin A). Determination). Not suitable for the crowd Inappropriate people: generally no special population. People without indications should not be tested. Adverse reactions and risks no.

Was this article helpful?

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.