tryptophan

More than 95% of the tryptophan in the human body is decomposed by the tryptophan-2,3-oxygenase of hepatocytes. When liver cells are damaged, the amount of this enzyme is reduced and the viability is reduced. Diseases caused by disorders of tryptophan metabolism can be found in liver function decline, tryptophanuria, hydroxykyrosinuria, and yellow urine urine. The latter three are hereditary diseases, which are due to color ammonia. The main metabolic pathways of acid to niacin and coenzyme I are impaired. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Rare. Normal value: Tryptophan: 28.52-72.28μmol/L Above normal: Diseases caused by disorders in the metabolism of tryptophan can be found in liver function decline, tryptophanuria, hydroxykynuria and uric aciduria. negative: Positive: Tips: The plasma amino acid concentration of normal people fluctuates day and night, with a peak at 8-10 in the morning and a trough at midnight. When taking blood, it is necessary to avoid the effects of digestion and absorption of food. It is better to take blood on an empty stomach in the morning. Normal value 28.52 to 72.28 μmol/L. Clinical significance Diseases caused by disorders of tryptophan metabolism can be found in liver function decline, tryptophanuria, hydroxykyrosinuria, and yellow urine urine. The latter three are hereditary diseases, which are due to color ammonia. The main metabolic pathways of acid to niacin and coenzyme I are impaired. Tryptophan in plasma is divided into two parts of free and albumin binding, about 90% of tryptophan is bound to albumin, and 10% is free tryptophan. More than 95% of the tryptophan in the human body is catalytically decomposed by tryptophan-2,3-oxygenase of hepatocytes. When the liver cells are damaged, the content of the enzyme and the enzyme activity are lowered, and the ability to decompose tryptophan is lowered to cause an increase in the concentration of tryptophan in the plasma. Tryptophanuria is characterized by physical and mental retardation, cerebellar ataxia, and skin photosensitivity. When the fasting serum serum tryptophan increased, when tryptophan was administered orally, the blood tryptophan was significantly increased, and it was not easy to return to the level before oral administration. At the same time, the discharge of tryptophan and indole acetic acid in the urine increased. Patients with hydroxy kynurenine have mild mental retardation, and dermatitis and oral ulcers caused by niacin deficiency can be seen in the baby. High results may be diseases: hepatic encephalopathy, fulminant liver failure precautions 1. The plasma amino acid concentration of normal people fluctuates day and night, with a peak at 8 to 10 in the morning and a trough at midnight. When taking blood, it is necessary to avoid the effects of digestion and absorption of food. It is better to take blood on an empty stomach in the morning. 2. If the specimen is not suitable for hemolysis, it may lead to a false increase in the measurement results. Inspection process The same as the fluorescence spectrometry. Not suitable for the crowd no. Adverse reactions and risks no.