cerebrospinal fluid protein

Cerebrospinal fluid is a colorless, transparent liquid that fills the ventricles, subarachnoid space, and central canal of the spinal cord. Cerebrospinal fluid is produced by the choroid plexus in the ventricles, similar in nature to plasma and lymph, and slightly viscous. Therefore, the detection of cerebrospinal fluid becomes one of the important auxiliary diagnostic tools when the central nervous system is damaged. Basic Information Specialist classification: neurological examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Rare. Normal value: Cerebrospinal fluid protein (adult waist pool): 150-450mg/L Cerebrospinal fluid protein (cerebellar medullary pool): 150-250mg/L Cerebrospinal fluid egg angstrom? 0-150mg / L Above normal: Increased protein content in the brain cerebrospinal fluid suggests that the blood-brain barrier is damaged, which is common in brain, spinal cord and meningitis, tumors, hemorrhage, etc., as well as brain softening, degenerative brain diseases, radiculopathy and diseases causing cerebrospinal fluid circulation obstruction. negative: Positive: Tips: Avoid eating sugar and processing food. Normal value Adult, waist pool 150 ~ 450mg / L, cerebellar medullary pool 150 ~ 250mg / L, intraventricular 50 ~ 150mg / L; newborn 400 ~ 1200mg / L; elderly 300 ~ 600mg / L. Clinical significance Abnormal results: increased protein content in the brain cerebrospinal fluid, suggesting that the blood-brain barrier is damaged, common in brain, spinal cord and meningitis, tumors, hemorrhage, etc., as well as brain softening, degenerative brain diseases, radiculopathy and cerebrospinal fluid circulation obstruction. Disease, etc., when the protein in the cerebrospinal fluid is above 10g/L, it will freeze in the form of yellow jelly after effluent, and there is protein-cell separation phenomenon, which is clinically called Froin syndrome, which is characteristic of subarachnoid obstructive cerebrospinal fluid. . People who need to be examined: patients with high levels of protein in cerebrospinal fluid. High results may be diseases: tuberculous myelitis, suppurative meningitis, intraspinal tuberculoma, pediatric spinal canal tumor, globular globular leukodystrophy, spinal canal granuloma, intraspinal abscess, anterior spinal artery Syndrome, syphilitic uveitis, intraspinal metastatic tumor considerations Inappropriate people: Other high-risk illnesses do not belong to this test. Contraindications before inspection: Avoid eating sugar and processing food. Requirements for inspection: Keep it in a relaxed state and cooperate with the doctor. Inspection process The Pan's test requires less specimens, high sensitivity, easy access to reagents, easy operation, and easy to observe. The precipitation is proportional to the protein content, and some normal cerebrospinal fluid can also have very weak positive results. The RossJine test mainly precipitates globulin, but the sensitivity is weak. The NoneApett test can detect globulin and albumin separately, but the operation is more complicated and rarely used. Not suitable for the crowd Patients with high intracranial pressure. Adverse reactions and risks Generally no harm.