Lund test

Replace the exogenous gastrointestinal hormone with a standard test meal to physiologically stimulate pancreatic secretion. Fatty acids and amino acids in the test stimulate the release of endogenous cholecystokinin in the duodenum and jejunum, and promote pancreatic secretion of pancreatic enzyme. The standard test meal has a capacity of 300 ml and contains 6% fat, 5% protein, and 15% sugar. The specific formulation is vegetable oil: 18 g, skim milk powder (or casein) 15 g, glucose 40 g, flavored syrup 15 g, and water to 300 ml. The subjects were fasting for more than 12 hours, and the duodenal drainage tube was inserted into the duodenum. The subjects drank 300 ml of the test meal within 3 to 5 minutes, and then collected the duodenal juice from the drainage tube in the supine position every 30 min1. The total was collected 4 times, and the trypsin activity was determined by colorimetry. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Pancreatic disease. Normal value: Trypsin activity: 22.69-51.25 U/h/kg Above normal: Rare. negative: Positive: Tips: Check with your doctor. Normal value 1. Enzymatic activity method 22.69 to 51.25 U/h/kg (body weight). 2. Concentration method 161 ~ 612mg / L (161 ~ 612μg / ml). Clinical significance Abnormal results: Trypsin activity was significantly reduced in pancreatic disease. The results of this test roughly reflect the degree of damage to the exocrine function of the pancreas, but the differential diagnosis of pancreatitis and pancreatic cancer is of little significance. This test does not measure total pancreatic secretion and bicarbonate secretion, requiring subjects to have normal gastrointestinal function. Need to check the crowd: inflammation, endocrine disorders. Low results may be diseases: chronic pancreatitis, pancreatic injury considerations Inappropriate population: This test should not be performed in acute pancreatitis or in the acute onset of suspected chronic pancreatitis. Patients after gastrectomy, vagus nerve resection, small intestine malabsorption, ampullary obstruction, etc. should not be tested. Contraindications before examination: loss of gastrointestinal function. Requirements for inspection: Check with your doctor. Inspection process Inspection method: replace the exogenous gastrointestinal hormone with a standard test meal, and physiologically stimulate the secretion of the pancreas. Not suitable for the crowd This test should not be performed in acute pancreatitis or in the acute onset of suspected chronic pancreatitis. Patients after gastrectomy, vagus nerve resection, small intestine malabsorption, ampullary obstruction, etc. should not be tested. Adverse reactions and risks Generally no complications and harm.