Zinc Sulfate Turbidity Test

Determination of plasma protein levels and analysis of its components is one of the important tests for liver disease. The principles of various serum colloidal stability tests are basically the same, but the reagents used are different, and the effects of promoting and inhibiting flocculation are different. Currently, the ZnTT test is commonly used in clinical practice. This test is also one of the serum turbidity and flocculation tests. The reaction principle is considered to be that the low concentration zinc sulfate buffer can cause salty precipitation of γ-globulin in the serum to show turbidity. The degree of turbidity is related to the content of γ-globulin in serum, and thus it is one of the liver function tests. This test, like other turbidity and flocculation tests, reflects the changes in protein, but the exact mechanism is not clear. And its sensitivity is not enough, the specificity is not good. There are now more specific and sensitive tests for examining protein and liver function, so they should be eliminated. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods, avoid heavy drinking. Normal value 2 to 12U. Clinical significance Abnormal result 1, significantly increased (1) liver cirrhosis, chronic hepatitis active phase, hepatocellular carcinoma, acute hepatitis, autoimmune hepatitis, and the like. (2) Non-hepatic diseases, chronic inflammation, collagen disease, tuberculosis, sarcoma-like disease, multiple myeloma, malignant tumors, etc. 2, significantly reduce intrahepatic bile stasis, extrahepatic bile stasis, multiple myeloma, with high proteinuria disease, long-term use of adrenocortical hormone, long-term use of immunosuppressants, anti-tumor drugs. Need to check the population of chronic inflammation, high proteinuria and other symptoms. High results may be diseases: liver cirrhosis, hepatitis, liver disease Inappropriate people: generally no special population. Taboo before the test: Do not eat too greasy, high-protein foods, avoid heavy drinking. So as not to affect the test results. Requirements for examination: should relax, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Inspection process 1. The patient's blood is taken and the serum is separated. 2. Take one tube of the same diameter as the standard tube, add 0.1ml of fresh serum, add 6ml of zinc sulphate barbital buffer, mix well, let stand for 30min at room temperature, and turbid with the standard tube, it will be turbid The number of degrees. Not suitable for the crowd There is usually no special population. Adverse reactions and risks No special complications.