phosphoglycerate kinase

Phosphoglycerate kinase (PGK) is a key enzyme in glycolysis and an essential enzyme for the survival of each organism. The lack of this enzyme can cause disorders such as metabolism of organisms. PGK is a monomeric, highly flexible glycolytic enzyme consisting essentially of two spherical structural thresholds that undergo significant conformational changes during binding to the substrate, ultimately resulting in a catalytic effect. The enzyme has only one type in some bacterial cells, and in most organisms, it contains two to three isoenzymes. These isoenzymes exhibit unique biological functions in addition to their different distribution in living organisms. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Neurological dysfunction, non-spherical erythrocyte hemolytic anemia. Normal value: Phosphoglycerate kinase: 18.31-22.97mU/molHb Above normal: Rare. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value 1. Customary unit 320±36.1U/gHb(±s); 9280±1047U/10) 12BRC (±s); 109±12.3 U/ml RBC (±s); 2. The legal unit is 20.64±2.33mU/molHb(±s); 9.28 ± 1.05 nU / RBC (± s); 109 ± 12.3 kU / LRBC (± s). Clinical significance The lack of Phosphoglycerate Kinase can cause nervous system dysfunction, non-spherical erythrocyte hemolytic anemia. Need to check the diagnosis of the type of anemia in the population. Low results may be diseases: hemolytic anemia considerations Inappropriate people: generally no special population. Forbidden before examination: Please inform the doctor about the recent medication and special physiological changes before the test. Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Requirements for examination: When taking blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Inspection process At present, with the increasing data in the PRINTS database, the identification of unknown protein sequences and the prediction of biological functions by protein fingerprinting are a highly specific bioinformatics means, and are increasingly being more Many scientific researchers have adopted it, but there are certain false positives in this method. This is something we need to pay attention to when analyzing the results. Not suitable for the crowd There is usually no special population. Adverse reactions and risks no.