creatine kinase

Creatine Kinase (CK) (ATP: Creatine N-phosphotransferase EC 2.7.3.2) is also known as phosphocreatine kinase (CPK). CK is mainly found in skeletal muscle, brain and heart muscle. Creatine kinase has a high value in the diagnosis of acute myocardial infarction. It is usually found in the cytoplasm and mitochondria of tissues such as the heart, muscles, and brain of animals. It is an important kinase directly related to intracellular energy function, muscle contraction, and ATP regeneration. It reversibly catalyzes creatine and ATP. The transphosphoryl reaction between. Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Found in hyperthyroidism. Normal value: Creatine kinase (male): 24-170 U/L Creatine kinase (female): 24-150 U/L Above normal: 1. Mainly diagnosed with myocardial infarction, the increase of CK is larger than that of AST and LDH, and it appears early, starts to increase in 2 to 4 hours, peaks in 12 to 48 hours, and returns to normal in 2 to 4 days. In particular, the diagnosis of myocardial ischemia and subendocardial myocardial infarction is more sensitive than other enzymes. Therefore, dynamic detection of CK changes can help to observe the condition and prognosis estimates. 2, also seen in the onset of progressive muscular dystrophy, viral myocarditis, multiple myocarditis, muscle injury or surgery, cerebrovascular disease, alcoholism, hypothyroidism, pulmonary infarction. negative: Positive: Tips: Before the test: Do not exercise vigorously, and ensure that foods containing EDTA, citric acid, fluoride and other anticoagulants are not eaten. Normal value Male 24-170U/L; female 24-150U/L. Clinical significance Abnormal result Increase: 1. Mainly diagnosed with myocardial infarction, the increase of CK is larger than that of AST and LDH, and it appears early, starts to increase in 2 to 4 hours, peaks in 12 to 48 hours, and returns to normal in 2 to 4 days. In particular, the diagnosis of myocardial ischemia and subendocardial myocardial infarction is more sensitive than other enzymes. Therefore, dynamic detection of CK changes can help to observe the condition and prognosis estimates. 2, also seen in the onset of progressive muscular dystrophy, viral myocarditis, multiple myocarditis, muscle injury or surgery, cerebrovascular disease, alcoholism, hypothyroidism, pulmonary infarction. Reduced: seen in hyperthyroidism. People who need to be tested Patients with myocardial ischemia, patients with myocardial infarction, and hyperthyroidism. High results may be diseases: pediatric viral myocarditis, tachycardia cardiomyopathy, organophosphorus pesticide poisoning, acute benign myositis in children, unstable angina pectoris, unstable angina pectoris in the elderly Before the test: Do not exercise vigorously, and ensure that foods containing anticoagulants such as EDTA, citric acid and fluoride are not eaten. At the time of examination: a small amount of serum is required. Not suitable for the crowd: no. Inspection process MB-CPK is mainly present in myocardial tissue and can be measured by immunological or electrophoretic methods. Not suitable for the crowd no. Adverse reactions and risks no.