erythrocyte lactate production rate

The increase of lactic acid in the body is mainly due to the lack of blood oxygen, which leads to the aerobic oxidation of pyruvate in the Krebs cycle. The rate of glycolysis increases, that is, the rate of reduction of pyruvate to lactic acid increases, and the ratio of lactic acid to pyruvate in the blood increases. Lactic acid increases. High lactateemia occurs. The determination of lactic acid is generally carried out by whole blood lactic acid spectrophotometry or plasma lactic acid colorimetry. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: normal. Normal value: Whole blood lactic acid: 0.5-1.7mmol/L Above normal: Lactic acidosis. negative: Positive: Tips: When you take blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Normal value Whole blood lactic acid 0.5 ~ 1.7mmol / L (5 ~ 15mg / dl). The lactic acid content in plasma is about 7% higher than that in whole blood. Cerebrospinal fluid lactic acid content is close to whole blood, but can be independently changed in central nervous system diseases. The amount of lactic acid excreted in 24 hours of urine was 5.5 to 22 mmol. Clinical significance Lactic acid is a glycolysis product in the absence of oxygen in the body. Both circulatory failure and respiratory failure may cause life-threatening lactic acidosis. At this time, the lactic acid in the blood usually exceeds 7mmol/L, even up to 25mmol/L. It is reported that in high lactate, the survival rate of low lactate level is 65%, and the survival rate of lactate level >10.5mmol/L is only 30%. . High results may be diseases: precautions for lactic acidosis Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process The examination process: blood is drawn, blood is taken for examination, and venous blood is generally taken, and blood is drawn by a doctor or a nurse. The amount of blood drawn is determined according to the difference of the test content and the number of items. The blood volume is usually 2-20 ml, and the maximum is not more than 50 ml. Enzyme specific examination is then used by the physician. Not suitable for the crowd no. Adverse reactions and risks no.