LDL-Cholesterol

The concentration of low-density lipoprotein cholesterol (LDL-C) is significantly positively correlated with the incidence of coronary heart disease. LDL-C-+ is an important indicator for evaluating the risk factors for coronary heart disease in individuals. There are many methods for determining LDL-C, and the currently accepted reference method is "β-quantitative", including centrifugation. Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: In the last meal before blood draw, avoid high-fat food and drinking, fasting 12 hours, extract forearm venous blood. Normal value Young people average about 2.7mmol / L (105mg / d); Middle and old aged people about 3.1mmol / L (120mg / dl); Greater than 4.14 mmol / L (> 160 mg / dl) is a significant increase. Clinical significance LDL-C is a very low-density lipoprotein converted from plasma, which is mainly synthesized intravascularly and degraded in the liver. The increase of LDL- mainly is the increase of cholesterol and may be accompanied by the increase of triglyceride, and the clinical manifestation is high blood lipoprotein type IIa or IIb. It can be seen that the diet is rich in cholesterol and saturated fatty acids, low thyroxine blood, nephrotic syndrome, and chronic. Renal failure, liver disease, diabetes, blood porphyria, anorexia nervosa, and pregnancy. LDL-C reduction can be seen in malnutrition, chronic anemia, myeloma, acute myocardial infarction, trauma, severe liver disease, hyperthyroidism, Dolman's disease or Reye syndrome. High results may be diseases: three high symptoms, high-lipoproteinemia precautions In the last meal before blood draw, avoid high-fat food and drinking, and fasting for 12 hours, extract forearm venous blood. Inspection process When the sample is mixed with the R1 enzyme developer, the polyanion and zwitterionic surfactant in the reagent protect LDL from reacting with the actual enzyme, acting only with non-LDL lipoprotein [including chylomicrons (CM), very low Density lipoprotein (VLDL) and high-density lipoprotein (LDL) react to release cholesterol, and the hydrogen peroxide produced by the enzyme is eliminated by the decomposition of peroxidase into water due to the lack of chromogen. Not suitable for the crowd no. Adverse reactions and risks no.