α2-pregnancy-related protein

SP3, also known as Pregnancy Zone Protein (PZP), is synthesized by liver and trophoblast cells. In vitro experiments have shown that certain cell lines of non-hepatic tumors can also be synthesized. The syncytium trophoblast, B lymphocytes and monocyte surface contain this protein. Not fully aware of its physiological functions. The proteolytic enzyme in the blood circulation is combined with SP3 to form a complex, which is subsequently cleared. SP3 and alpha 2 macroglobulin may be homologs. Basic Information Specialist classification: maternity check check classification: biochemical examination Applicable gender: whether women are fasting: fasting Analysis results: Below normal: Decreased serum levels The serum SP3 at 12 or 24 weeks of gestation is associated with a lower risk of spontaneous abortion than the corresponding level of normal pregnant women. Normal value: Serum α2-pregnancy-associated protein: 0-1.80g/L Above normal: Elevated serum levels can be seen in a variety of tumor and immune system diseases, inflammation, and treatment with estrogen. Joint testing with CEA and dynamic observation have certain clinical value for the prognosis of lung cancer and ovarian cancer. negative: Positive: Tips: Before the examination, the diet is light and alcohol is prohibited. Check for an empty stomach in the morning. Normal value Immunodiffusion method: The serum maternal <1.80 g / L, its level increased with the progress of pregnancy time. Fertilization began to rise within a few weeks, rising rapidly in the first 3 months, slowing down later, and averaging 1.00 g/L in the 9th week. Normal pregnant women can increase SP3 during pregnancy to 20 to 100 times that of non-pregnant women. The level dropped to <0.1 g/L at 6 weeks after delivery. Clinical significance 1, elevated serum levels can be found in a variety of tumor and immune system diseases, inflammation and treatment with estrogen. Joint testing with CEA and dynamic observation have certain clinical value for the prognosis of lung cancer and ovarian cancer. 2. Serum content reduction The serum SP3 at the 12th week or the 24th week of pregnancy is lower than the corresponding level of normal pregnant women, suggesting a risk of spontaneous abortion. Low results may be diseases: high lung cancer results may be diseases: ovarian cancer, spontaneous abortion precautions Serum should avoid interference with hemolysis and lipids. Inspection process The same as the immunodiffusion method. Not suitable for the crowd no. Adverse reactions and risks no.