α2-thermostable glycoprotein

α2-HS, also known as thermostable glycoprotein, is mostly synthesized by the liver and is a component of the bone matrix. The half-life in blood is 4 to 5 days. The immunoelectrophoresis position is slightly faster than binding to globin, between the Gc globulin and the haptoglobin. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Serum α2-HSG was significantly reduced in negative acute phase reaction protein infection, major surgery, malignant tumor, and malnutrition. Normal value: 2-2-heat stable glycoprotein: 400-850mg/L Above normal: It is elevated in acute hepatitis and persistent hepatitis, and some show no significant change in acute hepatitis. negative: Positive: Tips: Before the examination, the diet is light, alcohol is prohibited, and a good sleep is maintained. Check for an empty stomach in the morning. Normal value 400 ~ 850mg / L, the average value of 600mg / L. Clinical significance 1. Diagnosis of liver disease diagnosis and prognosis The literature reports that the changes of serum α2-HSG in patients with acute hepatitis are inconsistent. Some experimental results show that α2-HSG is elevated in acute hepatitis and persistent hepatitis, and some show no significant change in acute hepatitis, but significantly decrease in subacute hepatic necrosis. It was found that the serum α2-HSG of patients with subacute hepatic necrosis was significantly lower than that of survivors. Therefore, serum α2-HSG determination is helpful for early diagnosis of subacute hepatic necrosis and judgment of severity and prognosis of liver damage. 2. The serum α2-HSG was significantly decreased in the negative acute phase reaction protein infection, after major surgery, malignant tumor and malnutrition. Low results may be diseases: high hepatitis results may be diseases: precautions for malnutrition It is known that α2-HSG molecules exist in both N and L forms. Very sensitive to proteolytic enzymes. At present, its physiological function is not clear, and it has been proved that α2-HSG can reduce the response of lymphocytes to plant lectins and promote the conditioning effect. Inspection process The same as the immunodiffusion method. Not suitable for the crowd no. Adverse reactions and risks no.