3.8sα2-glycoprotein

3.8Sα2-glycoprotein is also called histidine-rich glycoprotein (HRG) because its amino acid composition contains a large amount of histidine residues. It mainly binds to heparin in the body and has a regulating effect on blood coagulation, fibrinolysis and immune function. In addition, it can also be combined with a small amount of heme and bilirubin, which is a multifunctional protein. Synthetic in hepatocytes. HRG can be used as an indicator to monitor the occurrence and development of graft versus host. Animal testing suggests that HRG is a negative acute reactant. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Common in liver dysfunction, sepsis, major surgery, hemodialysis, pre-eclampsia often accompanied by thrombosis, the serum HRG concentration is lower than normal pregnant women. Normal value: Serum 3.8sα2-glycoprotein: 50-150mg/L Above normal: Found in acute myocardial infarction, deep vein thrombosis. negative: Positive: Tips: Not suitable for the crowd: normal full-term newborn, normal pregnant women in the middle and late, normal women after oral contraceptives. Normal value Immunodiffusion method: Serum 50 ~ 150mg / L, the median is 90mg / L Platelet 231 ~ 486ng / 109 platelets Clinical significance Abnormal results: Decreased serum levels: common in liver dysfunction, sepsis, major surgery, hemodialysis; pre-eclampsia is often accompanied by thrombosis, serum HRG concentration is lower than normal pregnant women. Increased serum levels: seen in acute myocardial infarction, deep vein thrombosis. Patients with severe immunodeficiency (such as AIDS), graft-versus-host patients, and sepsis should be examined. Low results may be diseases: high results of sepsis may be diseases: precautions for acute myocardial infarction Unsuitable for the population: normal full-term newborns, normal middle and late pregnancy women, normal women after oral contraceptives. Inspection process Chemical examination was performed after venous blood draw. Not suitable for the crowd Normal term newborn, normal middle and late pregnancy, normal women after oral contraceptives. Adverse reactions and risks Generally no complications and harm.

Was this article helpful?

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.