Pilocarpine sweat test

The pilocarpine test is one of the methods of the sweat test. The secretion of sweat glands depends on the number of sweat glands, the functional state and the excitability of the sympathetic nerves in the site. Sweat dysfunction occurs as skin damage affects the sweat glands. After giving a certain amount of pilocarpine, the spinal cord horn cells, sympathetic ganglia and post-ganglionic fibers were stimulated to observe the sweating of the skin. Basic Information Specialist classification: skin examination classification: endocrine examination Applicable gender: whether men and women apply fasting: not fasting Including items: pilocarpine sweating test Tips: those who are allergic to pilocarpine are not suitable for this test. Normal value The skin is dampened by perspiration, and it is normal for iodine to turn blue and black. Clinical significance Abnormal results: 1. The skin is dark blue, and no obvious sweat is positive for the test, suggesting more sweating; the skin is light blue and weakly positive, suggesting a small amount of sweating; the skin becomes dark blue and a large amount of sweat is strongly positive. 2. The skin does not change color to negative, indicating no sweating. Patients who need to be examined for leprosy and other causes of skin damage, sweatlessness and other patients. Positive results may be diseases: no sweating, leprosy, skin problems Taboo before inspection: After an empty stomach or strenuous exercise. The iodine skin test and the pilocarpine skin test must be performed before the test. Apply iodine and sesame oil to the skin and the starch should be even, so as not to affect the test results. Requirements for inspection: 1. Be careful not to take pilocarpine. If you accidentally consume pilocarpine, you should induce vomiting or gastric lavage. Pay attention to the dosage. 2, sometimes need to check the body for the following diseases: patients with cholelithiasis or biliary tract disease (can cause changes in biliary smooth muscle tone), chronic obstructive pulmonary disease or chronic bronchitis patients (can cause respiratory resistance, bronchial smooth muscle tone or secretion Changes in liver and kidney dysfunction, hyperthyroidism, Parkinson's disease, peptic ulcer or gastrointestinal tract, kidney stones (may cause renal colic or ureteral reflux), cognitive decline or People with mental disorders (may affect the central nervous system), urinary tract obstruction, history of retinal detachment or risk of shedding. Inspection process Select normal skin and skin lesions, apply iodine, respectively. After drying, inject 0.1 ml of 1/1000 pilocarpine solution in two places, immediately sprinkle a thin layer of starch on it, after about 3 to 5 minutes, normal skin. Sweating, the starch immediately turns blue-violet, and if it does not sweat, the starch does not change color. Not suitable for the crowd Inappropriate crowd: 1. Those who are allergic to pilocarpine. 2. Patients with bronchial asthma. 3. Acute conjunctivitis or other ocular diseases that should not be retracted (such as acute iritis) are prohibited. Adverse reactions and risks Iodine allergies are contraindicated for this test, others generally have no special complications.